Background The optimal duration, safety, and benefit of preoperative chemotherapy in patients with colorectal liver metastases (CLM) are unclear. We evaluated the association between the duration of preoperative chemotherapy ...

The liver is the exclusive site of metastasis in approximately 30% to 50% of patients with stage IV colorectal cancer, whereas lung metastasis occurs in 10% to 20% of patients. No single study has specifically addressed ...