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Browsing by Author "Azar, Sami T."

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Browsing by Author "Azar, Sami T."

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  • The DD genotype of the ACE gene polymorphism is associated with diabetic nephropathy in type-1 diabetics 
    Azar, Sami T.; Zalloua, Pierre A.; Medlej, Rita; Halabi, George (2019-07-19)
    Genetic factors are involved in the development of diabetic nephropathy in type-1 diabetes. We are examining the association of the angiotensin-converting enzyme (ACE), insertion/deletion (I/D) polymorphism with the presence ...
  • Higher serum leptin level in women than in nen with type 1 diabetes 
    Azar, Sami T.; Salti, Ibrahim; Zantout, Mira S.; Shahine, Carmen H.; Zalloua, Pierre A. (2019-07-19)
    Leptin is the protein product of the obese (ob) gene, a lipostatic hormone that contributes to body weight regulation through suppressing appetite and/or stimulating energy expenditure in humans and/or rodents. In humans, ...
  • The I allele of the angiotensin converting enzyme I/D polymorphism confers protection against coronary artery disease 
    Abchee, Antoine; El-Sibai, Mirvat; Youhanna, Sonia; Yeretzian, Joumana S.; Hanine, Estephan; Makhoul, Nadine J.; Puzantian, Houry; Sawaya, Jaber; Nasrallah, Antoine; Rebeiz, Abdallah G.; Zreik, Tony G.; Azar, Sami T.; Zalloua, Pierre A. (2017-07-27)
    Background: Mutations in genes regulating lipid metabolism, vasoactivity, and coagulation are important modulators of coronary artery disease (CAD). Objective: This study investigated the association between allelic ...
  • Impact of seafood and fruit consumption on bone mineral density 
    Zalloua, Pierre A.; Hsu, Yi-Hsiang; Terwedow, Henry; Zang, Tonghua; Tang, Genfu; Li, Zhiping; Hong, Xiumei; Azar, Sami T.; Wang, Binyan; Bouxsein, Mary L.; Brain, Joseph; Cummings, Steven R.; Rosen, Clifford J.; Xu, Xiping (2019-07-18)
    Objectives Over the past decade, dietary choices and nutrition have proven to be major modulators of bone mineral density (BMD) in men and women. We investigated environmental determinants, specifically dietary habits, ...
  • No association between the −1031 polymorphism in the TNF-α promoter region and type 1 diabetes 
    Shbaklo, Hadia; Azar, Sami T.; Terwedow, Henry; Halaby, Georges; Naja, Roy P.; Zalloua, Pierre A. (2019-07-22)
    Tumor necrosis factor alpha (TNF-α) is an important immunomodulator and is believed to be involved in the development or progression of type 1 diabetes. In the following study, we evaluated TNF-α promoter ...
  • Predictors of coronary artery disease in the Lebanese population 
    Abchee, Antoine; Puzantian, Houry; Azar, Sami T.; Shbaklo, Hadia; Nasrallah, Antoine; Sawaya, Fadi J.; Alam, Samir; Zalloua, Pierre A. (2019-07-19)
    Background Coronary artery disease (CAD) is one of the major causes of morbidity and mortality in the world. The disease is determined by many risk factors such as age, gender, diabetes, dyslipidemia, smoking, as well as ...
  • Prevalence of asthmatic symptoms in Lebanese patients with type 1 diabetes and their unaffected siblings compared to age-matched controls 
    Taleb, Nadine; Bou Khalil, Pierre; Zantout, Mira S.; Zalloua, Pierre; Azar, Sami T. (2019-07-22)
    Patients with type 1 diabetes (a TH1 disease) have been reported to be at a lower risk of developing asthma (a TH2 disease). Both diseases are affected by environmental and genetic factors. Our objective is to examine this ...
  • WFS1 mutations are frequent monogenic causes of juvenile-onset diabetes mellitus in Lebanon 
    Zallloua, Pierre A.; Azar, Sami T.; Delepine, Marc; Makhoul, Nadine J.; Blanc, Herve; Sanyoura, May; Lavergne, Anne; Stankov, Karmen; Lemainque, Arnaud; Baz, Patrick; Julier, Cecile (2019-07-25)
    Most cases of juvenile-onset diabetes (JOD) are diagnosed as type 1 diabetes (T1D), for which genetic studies conducted in outbred Caucasian populations support the concept of multifactorial inheritance. However, this view ...