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Browsing by Author "Vauthey, Nicolas"

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Browsing by Author "Vauthey, Nicolas"

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  • Impact of Resection Status on Pattern of Failure and Survival After Pancreaticoduodenectomy for Pancreatic Adenocarcinoma 
    Raut, Chandrajit; Tseng, Jennifer; Sun, Charlotte; Wang, Huamin; Wolff, Robert; Crane, Christopher; Vauthey, Nicolas; Abdalla, Eddie; Lee, Jeffrey; Pisters, Peter; Evans, Douglas (2015-11-16)
    Objective: To better understand the impact of a microscopically positive margin (R1) on patterns of disease recurrence and survival after pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma. Summary Background ...
  • Is extended hepatectomy for hepatobiliary malignancy justified? 
    Abdalla, Eddie; Vauthey, Nicolas; Pawlik, Timothy; Arens, James; Nemr, Rabih; Wei, Steven; Kennamer, Debra; Ellis, Lee; Curley, Steven (2015-11-11)
    Background: Extended hepatectomy may be required to provide the best chance for cure of hepatobiliary malignancies. However, the procedure may be associated with significant morbidity and mortality. Methods: We ...
  • Laparoscopy for diagnosis and staging of hepatobiliary malignancies 
    Abdalla, Eddie; Aloia, Thomas; Vauthey, Nicolas (2015-11-11)
    Objective: To review the role of diagnostic laparoscopy (DL) for staging of malignant diseases of the liver and biliary tract. Methodology: Critical review of the current literature. Results: Analysis of the utility ...
  • Liver resection in the treatment of hepatocellular carcinoma 
    Abdalla, Eddie; Ribero, Dario; Thomas, Melanie; Vauthey, Nicolas (2015-11-12)
    Hepatocellular carcinoma is a leading cause of cancer death worldwide. Liver resection and liver transplantation remain the only options for cure. Since the indications for orthotopic liver transplantation are limited, ...
  • Liver-Directed Surgery for Metastatic Squamous Cell Carcinoma to the Liver 
    Pawlik, Timothy; Gleisner, Ana Luiza; Bauer, Todd; Reddy, Srinevas; Clary, Bryan; Martin, Robert; Scoggins, Charles; Tanabe, Kenneth; Michealson, James; Kooby, David; Staley, Charles; Schulick, Richard; Vauthey, Nicolas; Abdalla, Eddie; Curley, Steven; Choti, Micheal; Elias, Dominique (2015-11-16)
    Background The role of hepatic resection for metastatic squamous cell carcinoma (SCC) remains unknown. The current study evaluates the role of hepatic resection in patients with metastatic SCC to the liver. Methods Between ...
  • Monolobar Caroli's Disease and cholangiocarcinoma 
    Abdalla, Eddie; Forsmark, Christopher; Lauwers, Gregory; Vauthey, Nicolas (2015-11-09)
    Caroli's Disease (CD) is a rare congenital disorder characterized by cystic dilatation of the intrahepatic bile ducts. This report describes a patient with cholangiocarcinoma arising in the setting of monolobar CD. In spite ...
  • New paradigm in the management of liver-only metastases from colorectal cancer 
    Donadon, Matteo; Ribero, Dario; Morris-Stiff, Gareth; Abdalla, Eddie; Vauthey, Nicolas (2015-11-16)
    For patients with colorectal liver metastases, hepatic resection is the treatment of choice, and the 5-year survival rate following surgery now exceeds 50%. Timely multidisciplinary and multimodality approaches that may ...
  • Operative considerations in resection of hilar cholangiocarcinoma 
    Abdalla, Eddie; Parikh, Alexandre; Vauthey, Nicolas (2015-11-11)
    This article reviews the preoperative evaluation and operative considerations in patients with hilar cholangiocarcinoma. The preoperative evaluation is based on the imaging evaluation of the longitudinal and radial extent ...
  • Outcomes of Liver Transplantation in 490 Patients with Hepatocellular Carcinoma 
    Vauthey, Nicolas; Ribero, Dario; Abdalla, Eddie; Jonas, Sven; Bharat, Ankit; Schumacher, Guido; Lerut, Jan; Chapman, William; Hemming, Alan; Neuhaus, Peter (2015-11-16)
    Background The aim of this study was to compare the ability of staging systems (American Joint Committee on Cancer/Union Internationale contre le Cancer [AJCC/UICC], Japanese TNM, Pittsburgh, United Network for Organ ...
  • Pancreaticoduodenectomy with vascular resection 
    Abdalla, Eddie; Tseng, Jennifer; Raut, Chandrajit; Lee, Jeffrey; Pisters, Peter; Vauthey, Nicolas; Gomez, Henry; Sun, Charlotte; Crane, Christopher; Wolff, Robert; Evans, Douglas (2015-11-11)
    Major vascular resection performed at the time of pancreaticoduodenectomy (PD) for adenocarcinoma remains controversial. We analyzed all patients who underwent vascular resection (VR) at the time of PD for any histology ...
  • Pathologic Response to Preoperative Chemotherapy 
    Blazer III, Dan; Kishi, Yoji; Maru, Dipen; Shin Chun, Yun; Overman, Micheal; Fogelman, David; Eng, Cathy; Chang, David; Wang, Huamin; Zorzi, Daria; Ribero, Dario; Ellis, Lee; Glover, Katrina; Wolff, Robert; Curley, Steven; Abdalla, Eddie; Vauthey, Nicolas (2015-11-16)
    Purpose The primary goal of this study was to evaluate whether pathologic response to chemotherapy predicts patient survival after preoperative chemotherapy and resection of colorectal liver metastases (CLM). The secondary ...
  • Portal vein embolization 
    Abdalla, Eddie; Hicks, M.E.; Vauthey, Nicolas (2015-11-10)
    Background: Advances in surgery have reduced the mortality rate after major liver resection, but complications resulting from inadequate postresection hepatic size and function remain. Portal vein embolization (PVE) was ...
  • Portal vein embolization in preparation for major hepatic resection 
    Madoff, David; Abdalla, Eddie; Vauthey, Nicolas (2015-11-11)
    Portal vein (PV) embolization (PVE) is gaining acceptance in the preoperative management of patients selected for major hepatic resection. PVE redirects portal blood flow to the intended liver remnant to induce hypertrophy ...
  • Recent advances in the treatment and outcome of locally advanced rectal cancer 
    Abdalla, Eddie; Vauthey, Nicolas; Marsh, Robert; Zlotecki, Robert; Solorzano, Carmen; Bray, Elizabeth; Freeman, Mark; Lauwers, Gregory; Kubilis, Paul; Mendenhall, William; Copeland III, Edward (2015-11-09)
    Objective To compare the outcomes of treatment of locally advanced rectal cancer of the early era (1975–1990) with those of the late era (1991–1997). Background Preoperative therapy has been used in locally advanced ...
  • Recurrence and outcomes following hepatic resection, radiofrequency ablation, and combined resection/ablation for colorectal liver metastases 
    Abdalla, Eddie; Vauthey, Nicolas; Ellis, Lee; Ellis, Vicky; Pollock, Raphael; Hess, Kenneth; Curley, Steven; Broglio, Kristine (2015-11-10)
    Objective: To examine recurrence and survival rates for patients treated with hepatic resection only, radiofrequency ablation (RFA) plus resection or RFA only for colorectal liver metastases. Summary Background ...
  • Resection of Hepatic Colorectal Metastases Involving the Caudate Lobe 
    Abdalla, Eddie; Ribero, Dario; Pawlik, Timothy; Zorzi, Daria; Curley, Steven; Muratore, Andrea; Andres, Axel; Mentha, Gilles; Capussotti, Lorenzo; Vauthey, Nicolas (2015-11-12)
    Purpose: To examine clinical features and outcome of patients who underwent hepatic resection for colorectal liver metastases (LM) involving the caudate lobe. Patients and Methods: Consecutive patients who underwent ...
  • Results of a Single-Center Experience With Resection and Ablation for Sarcoma Metastatic to the Liver 
    Abdalla, Eddie; Pawlik, Timothy; Vauthey, Nicolas; Pollock, Raphael; Ellis, Lee; Curley, Steven (2015-11-12)
    Hypothesis A subset of patients with sarcoma liver metastasis may benefit from hepatic resection and/or ablation. Design Retrospective review of prospectively collected cancer center database records. Patients and ...
  • Risk factors for early death due to recurrence after liver resection for hepatocellular carcinoma: Results of a multicenter study 
    Abdalla, Eddie; Regimbeau, Jean-Marc; Vauthey, Nicolas; Lauwers, Gregory; Durand, Francois; Nagorney, David; Lkai, Iwao; Yamaoka, Yoshio; Belghiti, Jacques (2015-11-10)
    Background and Objectives: Recurrence after partial liver resection for hepatocel-lular carcinoma (HCC) is a major cause of death from this disease. To identify riskfactors for early death from recurrence after liver ...
  • Simultaneous Resections of Colorectal Cancer and Synchronous Liver Metastases 
    Reddy, Srinevas; Pawlik, Timothy; Zorzi, Daria; Gleisner, Ana; Ribero, Dario; Assumpc ao, Lia; Barbas, Andrew; Abdalla, Eddie; Choti, Micheal; Vauthey, Nicolas; Ludwig, Krik; Mantyh, Christopher; Morse, Micheal; Clary, Bryan (2015-11-16)
    Background The safety of simultaneous resections of colorectal cancer and synchronous liver metastases (SCRLM) is not established. This multi-institutional retrospective study compared postoperative outcomes after ...
  • Solitary colorectal liver metastasis 
    Abdalla, Eddie; Vauthey, Nicolas; Loyer, Evelyne; Ribero, Dario; Pawlik, Timothy; Wei, Steven; Zorzi, Daria (2015-11-12)
    Background Hepatic resection (HR) and radiofrequency ablation (RFA) have been proposed as equivalent treatments for colorectal liver metastasis. Hypothesis Recurrence patterns after HR and RFA for solitary liver ...