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Browsing by Author "Vauthey, Jean-Nicolas"

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Browsing by Author "Vauthey, Jean-Nicolas"

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  • Liver resection for liver metastases from nondigestive endocrine cancer 
    Andreou, Andreas; Brouquet, Antoine; Bharathy, Kishore; Perrier, Nancy; Abdalla, Eddie; Curley, Steven; Glanemann, Matthias; Seehofer, Daniel; Neuhaus, Peter; Vauthey, Jean-Nicolas; Aloia, Thomas (2015-11-20)
    Background For patients with hepatic nondigestive endocrine metastases (HNEM), the role of liver resection is not well-defined. Methods We reviewed outcomes for patients who underwent liver resection for HNEM at ...
  • Long-Term Survival After Multidisciplinary Management of Resected Pancreatic Adenocarcinoma 
    Katz, Matthew; Wang, Huamin; Fleming, Jason; Sun, Charlotte; Hwang, Rosa; Wolff, Robert; Varadhachary, Gauri; Abbruzzese, James; Crane, Christopher; Krishnan, Sunil; Vauthey, Jean-Nicolas; Abdalla, Eddie; Lee, Jeffrey; Pisters, Peter; Evans, Douglas (2015-11-17)
    Introduction Actual 5-year survival rates of 10–18% have been reported for patients with resected pancreatic adenocarcinoma (PC), but the use of multimodality therapy was uncommon in these series. We evaluated long-term ...
  • Long-term survival after surgical management of neuroendocrine hepatic metastases 
    Glazer, Evan; Tseng, Jennifer; Al-Refaie, Waddah; Solorzano, Carmen; Liu, Ping; Willborn, Katherine; Abdalla, Eddie; Vauthey, Jean-Nicolas (2015-11-19)
    Background:  Surgical cytoreduction and endocrine blockade are important options for care for neuroendocrine liver metastases. We investigated the long-term survival of patients surgically treated for hepatic neuroendocrine ...
  • Major hepatic resection for hepatocellular carcinoma with or without portal vein embolization 
    Palavecino, Martin; Chun, Yun; Madoff, David; Zorzi, Daria; Kishi, Yoji; Kaseb, Ahmed; Curley, Steven; Abdalla, Eddie; Vauthey, Jean-Nicolas (2015-11-18)
    Background Preoperative portal vein embolization (PVE) is performed to minimize perioperative risks of major hepatic resection for hepatocellular carcinoma (HCC), but its effects on tumor growth are ill defined. ...
  • Margin Status Remains an Important Determinant of Survival after Surgical Resection of Colorectal Liver Metastases in the Era of Modern Chemotherapy 
    Andreou, Andreas; Aloia, Thomas; Brouquet, Antoine; Dickson, Paxton; Zimmitti, Guiseppe; Maru, Dipen; Kopetz, Scott; Loyer, Evelyne; Curley, Steven; Abdalla, Eddie; Vauthey, Jean-Nicolas (2015-11-20)
    Objective To determine the impact of surgical margin status on overall survival (OS) of patients undergoing hepatectomy for colorectal liver metastases (CLM) after modern preoperative chemotherapy. Summary Background ...
  • A marking technique for intraoperative localization of small liver metastases before systemic chemotherapy 
    Zalinski, Stephanie; Abdalla, Eddie; Mahvash, Ameen; Vauthey, Jean-Nicolas (2015-11-18)
    Preoperative chemotherapy is increasingly used prior to resection of colorectal liver metastases (CLM). Since some of these lesions may disappear or may be hardly detectable with intraoperative ultrasound (IOUS), we describe ...
  • Morbidity of Staged Proctectomy After Hepatectomy for Colorectal Cancer 
    Tzeng, Ching-Wei; Aloia, Thomas; Vauthey, Jean-Nicolas; Chang, George; Ellis, Lee; Feig, Barry; Curley, Steven; Skibber, John; Abdalla, Eddie; You, Nancy; Rodriguez-Bigas, Miguel (2015-11-20)
    Background Proctectomy after hepatectomy, or the reverse approach, is an alternative to traditional sequencing for advanced liver metastases with asymptomatic colorectal primary tumors. We sought to evaluate the surgical ...
  • Neither Neoadjuvant nor Adjuvant Therapy Increases Survival After Biliary Tract Cancer Resection with Wide Negative Margins 
    Glazer, Evan; Lui, Ping; Abdalla, Eddie; Vauthey, Jean-Nicolas; Curley, Steven (2015-11-20)
    Background We investigated the role of neoadjuvant/adjuvant therapies on survival for resectable biliary tract cancer. We hypothesized that neoadjuvant and adjuvant therapy should improve the survival probability in these ...
  • One Hundred Years After “Carcinoid” 
    Yao, James; Hassan, Manal; Phan, Alexandria; Dagohy, Cecile; Leary, Colleen; Mares, Jeannette; Abdalla, Eddie; Fleming, Jason; Vauthey, Jean-Nicolas; Rashid, Asif; Evans, Douglas (2015-11-17)
    Purpose Neuroendocrine tumors (NETs) are considered rare tumors and can produce a variety of hormones. In this study, we examined the epidemiology of and prognostic factors for NETs, because a thorough examination of neither ...
  • Portal Vein Embolization in Hilar Cholangiocarcinoma 
    Palavecino, Martin; Abdalla, Eddie; Madoff, David; Vauthey, Jean-Nicolas (2015-11-18)
    In patients with hilar cholangiocarcinoma, extended hepatectomy and caudate lobe resection are often performed to achieve an R0 resection. In patients whose standardized future liver remnant is less than or equal to 20% ...
  • Post-Therapy Pathologic Stage and Survival in Patients With Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant Chemoradiation 
    Estrella, Jeannelyn; Rashid, Asif; Fleming, Jason; Katz, Matthew; Lee, Jeffrey; Wolff, Robert; Varadhachary, Gauri; Pisters, Peter; Abdalla, Eddie; Vauthey, Jean-Nicolas; Wang, Hua; Gomez, Henry; Evans, Douglas; Abbruzzese, James; Wang, Huamin (2015-11-20)
    BACKGROUND: Neoadjuvant chemoradiation before surgery is an emerging treatment modality for pancreatic ductal adenocarcinoma (PDAC). However, analysis of prognostic factors is limited for patients with PDAC treated with ...
  • Preoperative Bevacizumab Does Not Significantly Increase Postoperative Complication Rates in Patients Undergoing Hepatic Surgery for Colorectal Cancer Liver Metastases 
    Kesmodel, Susan; Ellis, Lee; Lin, E.; Chang, George; Abdalla, Eddie; Kopetz, Scott; Vauthey, Jean-Nicolas; Rodriguez-Bigas, Miguel; Curley, Steven; Feig, Barry (2015-11-17)
    Purpose Although bevacizumab (BV) increases survival rates when used with chemotherapy (CTX) in patients who have metastatic colorectal cancer (CRC), an increase in wound complications has been observed in patients who ...
  • Preoperative Gemcitabine and Cisplatin Followed by Gemcitabine-Based Chemoradiation for Resectable Adenocarcinoma of the Pancreatic Head 
    Varadhachary, Gauri; Wolff, Robert; Crane, Christopher; Sun, Charlotte; Lee, Jeffrey; Pisters, Peter; Vauthey, Jean-Nicolas; Abdalla, Eddie; Wang, Huamin; Staerkel, Gregg; Ross, William; Tamm, Eric; Bhosale, Priya; Krishnan, Sunil; Das, Prajnan; Ho, Linus; Xiong, Henry; Abbruzzese, James; Evans, Douglas (2015-11-17)
    Purpose We conducted a phase II trial of preoperative gemcitabine and cisplatin chemotherapy in addition to chemoradiation (Gem-Cis-XRT) and pancreaticoduodenectomy (PD) for patients with stage I/II pancreatic adenocarci ...
  • Pretreatment assessment of hepatocellular carcinoma: expert consensus statement 
    Vauthey, Jean-Nicolas; Dixon, Elijah; Abdalla, Eddie; Helton, Scott; Pawlik, Timothy; Taouli, Bachir; Brouquet, Antoine; Adams, Reid (2015-11-19)
    Staging of hepatocellular carcinoma (HCC) is complex and relies on multiple factors including tumor extent and hepatic function. No single staging system is applicable to all patients with HCC. The staging of the American ...
  • A Proposed Staging System for Intrahepatic Cholangiocarcinoma 
    Nathan, Hari; Aloia, Thomas; Vauthey, Jean-Nicolas; Abdalla, Eddie; Zhu, Andrew; Schulick, Richard; Choti, Micheal; Pawlik, Timothy (2015-11-18)
    The American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) staging system for liver cancer is based on data exclusively derived from hepatocellular carcinoma (HCC) patients and thus may be ...
  • Radiation treatment outcomes for unresectable hepatocellular carcinoma 
    Skinner, Heath; Sharp, Hadley; Kaseb, Ahmed; Javle, Milind; Vauthey, Jean-Nicolas; Abdalla, Eddie; Declos, Marc; Das, Prajnan; Crane, Christopher; Krishnan, Sunil (2015-11-20)
    Background. Hepatocellular carcinoma is one of the most common cancers worldwide. Data regarding the use of radiotherapy is limited in patients from populations without endemic viral hepatitis. We examine the outcomes for ...
  • Repeat hepatectomy for recurrent colorectal liver metastases is associated with a high survival rate 
    Andreou, Andreas; Brouquet, Antoine; Abdalla, Eddie; Aloia, Thomas; Curley, Steven; Vauthey, Jean-Nicolas (2015-11-19)
    Background:  The outcome after a repeat hepatectomy for recurrent colorectal liver metastases (CLM) is not well defined. The present study examined the morbidity, mortality and long-term survivals after a repeat hepatectomy ...
  • Resection of At-Risk Mesenteric Lymph Nodes Is Associated with Improved Survival in Patients with Small Bowel Neuroendocrine Tumors 
    Landry, Christine; Lin, Heather; Phan, Alexandria; Charnsangavej, Chusilp; Abdalla, Eddie; Aloia, Thomas; Vauthey, Jean-Nicolas; Katz, Matthew; Yao, James; Fleming, Jason (2015-11-20)
    Background Neuroendocrine tumors of the small intestine commonly metastasize to regional lymph nodes (LNs). Single-institution reports suggest that removal of LNs improves outcome, but comprehensive data are lacking. We ...
  • Resection of liver metastases from breast cancer 
    Abbott, Daniel; Brouquet, Antoine; Mittendorf, Elizabeth; Andreou, Andreas; Meric-Bernstam, Funda; Valero, Vicente; Green, Marjorie; Kuerer, Henry; Curley, Steven; Vauthey, Jean-Nicolas; Abdalla, Eddie; Hunt, Kelly (2015-11-20)
    Background The oncologic benefit of resecting liver metastases in patients with breast cancer is unclear. This study was performed to identify predictors of survival after hepatectomy. Methods Between 1997 and ...
  • Risk of venous thromboembolism outweighs post-hepatectomy bleeding complications 
    Tzeng, Ching-Wei; Katz, Matthew; Fleming, Jason; Pisters, Peter; Lee, Jeffrey; Abdalla, Eddie; Curley, Steven; Vauthey, Jean-Nicolas; Aloia, Thomas (2015-11-20)
    Background: Historically, liver surgeons have withheld venous thromboembolism (VTE) chemoprophylaxis due to perceived postoperative bleeding risk and theorized protective anticoagulation effects of a hepatectomy. The ...